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University of Florida - Postdoctoral position in Human Molecular Genetics/Epigenetics

by Ed Hagen last modified Jun 12, 2014 02:07 PM
A postdoctoral position (two years at least) is available in Connie Mulligan's lab at the University of Florida.


Two NSF-funded projects are currently ongoing and the successful candidate can work on one or both: 1) Examination of DNA methylation patterns in mothers and newborns from the Democratic Republic of Congo (DRC) to test whether epigenetic alterations mediate the effects of maternal exposure to stressors on fetal development and neonatal health. Specifically, we are testing if epigenetic modifications may mediate changes in gene expression in infants or mothers that result from maternal trauma and material deprivation associated with the war in the DRC. More broadly, we are interested in the idea that behavior and complex phenotypes may be shaped by early life experiences that alter gene expression through epigenetic alterations. See https://www.landesbioscience.com/journals/epigenetics/2012EPI0162R-X.pdf 2) Investigation of the genetic and cultural underpinnings of complex diseases that exhibit racial inequalities, using hypertension in African-Americans as a model phenotype. We are combining the analysis of genome-wide SNPs, genetic ancestry estimates, and epigenetic variation with sociocultural data including experience of discrimination and social network analysis. By combining genetic and socio-cultural data, our goal is a more comprehensive investigation of complex disease and racial disparities than is possible with only one type of data. See related study -http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0006821

Qualifications: A PhD and a strong background in generation of genetic data (microarray analysis, DNA sequencing, SNP detection, etc.) and data analysis (gene association analysis, regression analysis, genetic ancestry estimation, linkage analysis, etc) are essential. Experience generating methylation data or additional computational experience (e.g. computer programming, simulation analysis, etc) is a plus. In addition to the projects listed above, there are excellent opportunities for the successful candidate to develop new lines of research as well as productive collaborations outside the lab.

The University of Florida is a leading research institution with a university-wide commitment to genetics research. The Department of Anthropology (www.anthro.ufl.edu) has 30 full-time faculty with diverse interests and a very strong biological subfield, with emphases on molecular, paleo, and forensic anthropology.  The department is one of the top rated programs in the country (6th among public institutions, 11th overall). The University of Florida Genetics Institute (www.ufgi.ufl.edu) is an inter-college entity with a new research building intended to enhance opportunities for collaboration. Gainesville is located in north central Florida (away from the hurricanes!), with average temperatures ranging from 45F to 90F. Beaches on the gulf and Atlantic coast are ~ 1½ hours away.

To apply: via email, send a CV, a statement of research interests, and the names and contact information (including email and phone) for three references. Applications and inquiries should be addressed to Connie Mulligan at cmulligan@ufl.edu

Review of materials will begin immediately and will continue until the position is filled. Start date is flexible and can start as early as August, 2014. Salary is commensurate with experience. Position may be extended for a total of three years. Informal inquiries prior to submitting a formal application are welcome. AA/EOE.

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