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University of Arizona Postdoctoral Fellowship in Bioinformatics of Next-Generation Sequencing and Disease

by Ed Hagen last modified Jun 07, 2012 01:16 PM expired
The University of Arizona Genetics Core (UAGC) in cooperation with Michael Hammer’s Lab in the ARL Division of Biotechnology at the University of Arizona is seeking a post-doctoral fellow interested in joining our research and technology team with emphasis on next generation approaches to diagnosing severe sporadic diseases in children, such as those involving epilepsy, autism, and other neurological/neuromuscular disorders. The position involves gene discovery and mapping using exome and whole genome sequencing and the characterization of newly identified disease genes and pathways.


The candidate will work with groups housed in both the UAGC nextgen core facility in the BIO5 Keating Building and in the Hammer lab.  The candidate will (a) implement workflows for whole-exome and whole-genome sequence data, (b) perform bioinformatics analysis in collaboration with our research group and various clinicians within the University Medical Center (UMC), and (c) develop new methods and approaches for the analysis of whole genome sequence data. The workflows will include methods for pre-processing, identification of sequence variants, comparisons to and integration with public databases, statistical analyses, and data visualization. The candidate will use these workflows to analyze data and to associate variants with both monogenic and complex diseases. The candidate will be expected to author scientific publications based on results of data analysis and on methods that have been developed.


We are looking for an enthusiastic communicative team player with 

• a PhD in a relevant scientific discipline;
• strong background in bioinformatics;
• experience with the analysis of next generation sequence data is very useful but not mandatory;
• experience with the statistical packages such as R
• good programming skills (e.g., Perl, Java) and knowledge of Unix
• good English language and communicative skills


All applicants must apply through the University of Arizona online application process by completing an appointed personnel application with contact information for three references and attaching a letter of interest and curriculum vitae. To view the on-line posting and to apply, go to www.uacareertrack and search postings using job #50278, or go to the quick link at The posting will remain open until filled, and review of applications will begin June 6, 2012.

In addition to completing the required online application process, qualified candidates are encouraged to email curriculum vitae and statement of interest to, attention: Dr. Michael Hammer, with “Postdoc “ in the subject line.

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